Post-implantation radiation therapy in head and neck cancer patients : a literature review.

The aim of this systematic review was to assess the outcomes of implants placed during ablative surgery in patients with HNC who underwent postoperative radiation therapy. Materials and methods : a review of the literature published between january 2014 and june 2019 was conducted. A PubMed search i...

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Auteurs principaux : Koudougou Carine (Auteur), Hoornaert Alain (Directeur de thèse)
Collectivités auteurs : Université de Nantes 1962-2021 (Organisme de soutenance), Université de Nantes Département odontologie (Organisme de soutenance)
Format : Thèse ou mémoire
Langue : anglais
Titre complet :  Post-implantation radiation therapy in head and neck cancer patients : a literature review. / Carine Koudougou; sous la direction de Alain Hoornaert
Publié : 2019
Description matérielle : 1 vol. ( 25 f.)
Note de thèse : Mémoire pour le diplôme d'université en implantologie orale. : Implantologie. : Nantes, : 2019
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Résumé : The aim of this systematic review was to assess the outcomes of implants placed during ablative surgery in patients with HNC who underwent postoperative radiation therapy. Materials and methods : a review of the literature published between january 2014 and june 2019 was conducted. A PubMed search identified all of the comparative studies evaluating the outcomes of primary implants in patients who underwent postoperative radiation therapy. Implants placed after radiation therapy and implants placed in reconstructed jaws were excluded. Results : 4 comparative studies were eligible for inclusion in the review, involving 755 native mandible primary implants. The overall survival rate with post-implantation radiation therapy was 89,4% versus 90,8% in implants for whom the implant surgery was carried out one year after completion of radiation therapy. In patient with primary implants that did not undergo additional radiation, the survival rate was 97,1%. One autor reported the radiation dose recieved by each implant, wich varied from 20 to 68 Grays. In 61 irradiated implants, 2 implants that recieved a radiation dose between 20 and 40 Grays were lost. The overall succes of implant-retained overdenture in patients with radiation therapy performed post-implantation was 67,4% versus 93,1% in patients with implant surgery that was carried out one year after the completion of radiation therapy. In patients with primary implants that did not undergo additional radiation, the overall succes of implant-retained overdenture was 74,9%. Conclusion : Although the outcomes for implant survival rates appear to be positive for irradiated implants the succes of implant-retained overdenture remains hard to predict. There is a need for more scientific data to accurately identify the patients for whom the risk-benefit ratio supports early implantation.
Bibliographie : Bibliogr. f. 22-25