Drug resistance in the treatment of cancer
Enregistré dans:
Autres auteurs : | , |
---|---|
Format : | Livre |
Langue : | anglais |
Titre complet : | Drug resistance in the treatment of cancer / edited by Herbert M. Pinedo and Giuseppe Giaccone |
Publié : |
Cambridge, U.K., New York :
Cambridge University Press
, c1998 |
Description matérielle : | xvi, 323 p. |
Collection : | Cancer, clinical science in practice |
Contenu : | Resistance mechanisms to antimetabolites. Resistance to antitumor alkylating agents and cisplatin. The MDR genes. Topoisomerase genes and resistance to topoisomerase inhibitors. Genes that modulate apoptosis: major determinatns of drug resistance. Clinical implications of drug resistance. The reversal of multidrug resistance. Effect of dose and schedule on chemotherapeutic drug resistance. Circumvention of drug resistance by high-dose chemotherapy in solid tumors. Enhancing drug effectiveness by gene transfer |
Sujets : |
Chargement en cours