Introduction to mass spectrometry : instrumentation, applications, and strategies for data interpretation

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Détails bibliographiques
Egalement en ligne : En ligne Via Introduction to mass spectrometry
Auteurs principaux : Watson J. Throck (Auteur), Sparkman Orrin David (Auteur)
Format : Livre
Langue : anglais
Titre complet : Introduction to mass spectrometry : instrumentation, applications, and strategies for data interpretation / J. Throck Watson,... O. David Sparkman,...
Édition : 4th edition
Publié : Hoboken (N.J.) : J. Wiley & sons , cop. 2007
Description matérielle : 1 vol. (XXIV-818 p.)
Sujets :
Documents associés : Autre format: Introduction to mass spectrometry
  • Chapter 1: Introduction.
  • I. What is Mass Spectrometry.
  • II. History.
  • III. Applications.
  • IV. The Data of Mass Spectrometry and Its Presentation.
  • V. Definition of Terms.
  • Chapter 2: The Mass Spectrometer.
  • I. Introduction.
  • II. Ion Guides.
  • III. Types of m/z Analyzers.
  • IV. Calibration of the m/z Scale.
  • V. Ion Detection.
  • VI. Vacuum Systems.
  • Chapter 3: Mass Spectrometry/Mass Spectrometry.
  • I. Introduction.
  • II. Ion Dissociation.
  • III. Instrumentation for MS/MS.
  • IV. Specialized Techniques and Applications.
  • V. Identification of Unknowns from CAD Data.
  • Chapter 4: Inlet Systems.
  • I. Introduction.
  • II. Batch Inlets.
  • III. Continuous Inlets.
  • IV. Ionization Inlet Systems.
  • V.Speciality Interfaces.
  • Chapter 5: Strategies for Data Interpretation (Other than Fragmentation).
  • I. Introduction.
  • II. Some Important Definitions.
  • III. The Possible Information That Can be Obtained from the Mass Spectrum.
  • IV. Elemental Composition of an Ion and the Ratios of Its Isotope Peaks.
  • V. Identifying the Molecular Mass of an Analyte.
  • VI. Recognition of Spurious Peaks in the Mass Spectrum.
  • VII. Obtaining Structural Information from Mass Spectra.
  • Chapter 6: Electron Ionization.
  • I. Introduction.
  • II. Ionization Process.
  • III. Strategy for Data Interpretation.
  • IV. Types of Fragmentation Pathways.
  • V. Representative Fragmentations (Spectra) of Classes of Compound.
  • VI. Library SearchVII. Summary of Interpretation of EI Mass Spectra.
  • Chapter 7: Chemical Ionization.
  • I. Introduction.
  • II. Description of the Chemical Ionization Source.
  • III. Production of Reagent Ions from Various Reagent Gases.
  • IV. Positive-Ion Formation Under CI.
  • V. Negative-Ion Formation under CI.
  • VI. Data Interpretation and Systematic Studies of CI.
  • VII. Ionization by Charge Exchange.
  • VIII. Atmospheric Pressure Chemical Ionization
  • IX. Desorption Chemical Ionization .
  • X. General Applications.
  • Chapter 8: Electrospray Ionization.
  • I. Introduction.
  • II. Operating Principles.
  • III. Appearance of ESI Mass Spectra and Data Interpretation.
  • IV. ESI with High Mass Resolving Power.
  • V. Implementations of Electrospray.
  • VI. Effect of Composition and Flowrate of Analyte Solution.
  • VII. Special Applications.
  • VIII. General Applications.
  • Chapter 9: MALDI.
  • I. Historical Perspective and Introduction.
  • II. Operating Principles.
  • III. Sample Handling.
  • IV. Special Instrumental Techniques.
  • V. Representative Applications.
  • Chapter 10: GC/MS.
  • I. Introduction to GC.
  • II. Sample Handling.
  • III. Instrument Requirements for GC/MS.
  • IV. Operational Considerations.
  • V. Sources of Error.
  • VI. Representative Applications of GC/MS.
  • Chapter 11: Liquid Chromatography/Mass Spectrometry.
  • I. Introduction.
  • II. Historical Milestones in the Development of the Interface.
  • III. Currently Viable Versions of the Interface.
  • IV. Operational Considerations (Special Operation of LC under MS Conditions).
  • V. Applications.
  • Chapter 12: Analysis of Proteins and other Biopolymers.
  • I. Proteins.
  • II. Oligonucleotides.
  • III. Carbohydrates.